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Key Features

FireflyDX-PortableTM At-a-Glance

  • Slated to be ExcitePCR's first commercially available product, the FireflyDX-PortableTM is a bookbag-sized system designed to provide integrated sample purification, biological analysis, and wireless communication of pathogen detection results, within 30 minutes or less. 
  • Uses real-time TaqMan® Polymerase chain reaction (PCR) at industry-standard reaction volumes.
  • Incorporates single-use, disposable cartridges with pre-programed RFID chips (no end-user programing or setup required).
  • The FireflyDX-Portable operates with any commercial assay, including those used by the Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO). An assay agnostic open platform, the FireflyDX-Portable utilizes a cartridge-based system that can test for any bio-threat, with no need to bring new assays to the U.S. Food and Drug Administration (FDA) for clearance, or any other regulatory body. 
  • Reagents and waste are all contained within a FireflyDX cartridge for containment and archival purposes.
  • Data is processed in realtime and communicated wirelessly from the FireflyDX-Portable.
  • The FireflyDX-Portable is designed for resource-limited areas and operation by minimally trained personnel.

 

 

 

FireflyDX-HandheldTM At-a-GlanceFirefly DX 

  • The FireflyDX-HandheldTM is essentially a handheld laboratory designed to provide integrated sample purification, biological analysis, and wireless communication of results, with no additional steps or equipment required.
  • Uses real-time TaqMan® Polymerase chain reaction (PCR) at industry-standard reaction volumes.
  • Incorporates single-use, disposable cartridges with pre-programed RFID chips (no end-user programing or setup required).
  • Operates with any commercial assay, including those used by Center for Disease Control (CDC) and the World Health Organization (WHO). The FireflyDX-Handheld is an agnostic, cartridge-based system that can test for any bio-threat, with no need to bring new assays to the U.S. Food and Drug Administration (FDA) for clearance, or any other regulatory body. 
  • Reagents and waste are all contained within a FireflyDX cartridge for containment and archival purposes.
  • Data is processed in realtime and communicated wirelessly from the FireflyDX-Handheld.
  • The FireflyDX-Handheld is designed for resource-limited areas and operation by minimally trained personnel.

 

 

 

 

Firefly DX CartridgeFireflyDX Cartridge At-a-Glance

  • Single-use, disposable cartridge currently running full sample preparation on breadboard prototype
  • Integration of ultrasonic sample lysis, nucleic acid purification, and PCR amplification with realtime detection
  • Sample purification and PCR amplification demonstrated across multiple organisms:
    • Zika Virus
    • Ebola
    • BWA agents (Ba, Yp, Ft)
  • Multiple organisms, cont.
    • Influenza A and B
    • Clinical and Environmental samples (E. coli)
    • Clinical (HPV)
    • Antibiotic resistant bacteria (MRSA, MSSA, C. diff)
  • Sample types processed: whole blood, nasal swabs, buccal swabs, simulated urine, environmental at standard volumes